CJ-VOLUME 03 ISSUE 02 MARCH 2013


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Volume 3 Issue 2, March 2013

Chemistry Journal

ISSN

2049-954X

Publication Frequency

6 Issues per year

Pages

44-80

Publication History


Original Articles

Multiple Patterns in Mixed Substrate B-Z System

Rohit Srivastava and P.K. Srivastava

Pages 44-49


Conductometric Study of Charge Transfer Complex Formation for the Determination of Aripirazole, Sumatriptan Succinate, Lamivudine and Rabeprazole Sodium

Magda Ayad, Hisham Abdellatef, Mervat  Hosnyand Nagla  Kabil

Pages 50-58


Thermochemistry of Heteroatomic Compounds: Some Thermodynamic Aspects of Combustion and Formation of Carbohydrates of Different Structures

Vitaly Ovchinnikov

Pages 59-65


Selective and Efficient Etherification of Secondary Cinnamyl Alcohols in the Presence of Iodine Catalyst and Evaluation of their Anti-Candida Activity

Anjaneyulu Kasa, Ravi Varala, Prabhuling M. Swami and Pudukulthan Zubaidha
Pages 66-74

Structural Study of PbO-PbF2-B2O3 Glass System Doped With V2O5 through Spectroscopic and Magnetic Properties 

P. Bhavani, T.V. Nagalakshmi, A.W. Iqbal and K.A. Emmanuel 
Pages 75-80
 

Title

Determination of Electrochemical Degradation of E102 Dye at Lead Dioxide-Doped Carbon Electrodes Using Some Potentiometric and Spectrophotometric Methods

Abstract

Multiple patterns have been investigated in BZ type mixed organic substrate (adipic acid/ethyl acetoacetate/ceric ammonium sulphate/ferroin/bromate/ sulph-uric acid system) at ambient conditions. The system shows four different types of pattern separated by null period. The pattern is found to be dependent on initial concentration of reactant and temperature. Microphotographs of fourth pattern show the DLA type nature. The Fourier Transform Infrared (FT-IR) spectroscopy of DLA-Grass like branched pattern shows the presence of close ring and metal complexes.

Keywords

Multiple Pattern, Non-equilibrium Crystallization, Self-organization, DLA Pattern

 

Title

Conductometric Study of Charge Transfer Complex Formation for the Determin-ation of Aripirazole, Sumatriptan Succinate, Lamivudine and Rabeprazole Sodi-um

Abstract

Two simple, accurate and rapid conductometric methods were developed for the determination of Aripirazole (Ι), Sumatriptan Succinate (II), Lamivudine (III) and Rabeprazole sodium (ΙV) in pure form as well as in their pharmaceutical formulatio-ns, where (I) is 7-{4-(4-(2,3-dichlorophenyl)-1- piprazinyl) butoxy}-3,4-dihydro-2 (1H)-quinolinone, (II) is 3-[2-(Dimethylamino) ethyl] –N-methyl-1H indole-5-metha-ne sulphonamide succinate, (III) is 4-amino-1-{(2R,5S)-2-(hydrox-ymetyl)- 1,3-oxathiolan-5-yl}-1,2-dihydropyrimidin-2-one, (IV) is 2-{{{4-(3-methoxypropoxy) -3-methyl-2-pyrid-ninyl} me -thyl}sulfinyl}-1H-benzimidazole sodium salt. These meth-ods were based on the formation of charge transfer complexes between the studied drugs, as n-electron donors, and p-chloranilic acid (PCA); 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ), as π-acceptors. Factors affecting the reaction, specifically reagent concentration and solvent type, were carefully studied in concentration range of 80-300 µg/mL, (4-15 mg/50 mL). The accuracy of the current methods was indicated by excellent recovery and low standard deviation. These methods were further applied successively to pharmaceutical formulations containing the mentioned drugs and the results obtained were favourably compared with those obtained using the reference methods.

Keywords

Conductometric Titration, Charge Transfer Complex, PCA, DDQ

Title

Thermochemistry of Heteroatomic Compounds: Some Thermodynamic Aspects of Combustion and Formation of Carbohydrates of Different Structures

Abstract

The linear equation of a general view DYо = i ± f (N - g), where DYо  can be a free energy or heat of combustion orformation, entropy and the heat of capacity, para-meters, i and f are correlation factors, describing the interdependence between thermodynamic functions of sugars and their numbers (N) of valence electrons except the numbers of lone electron pairs (g) of heteroatoms in them, has been applied for calculation of sugars of a various structure. The obtained results can be used for an estimation of the energy transfer in living systems by the means of phosphorus containing sugars like adenosine-triphosphate (ATP).

Keywords

Sugar, Carbohydrate, Combustion, Formation, Free Energy, Heat, Entropy, Heat Capacity

Title

Selective and Efficient Etherification of Secondary Cinnamyl Alcohols in the Presence of Iodine Catalyst and Evaluation of their Anti-Candida Activity

Abstract

An efficient and selective method for the conversion of secondary cinnamyl alcohols into their corresponding ethers using molecular iodine as catalyst under solvolytic condition is described. The synthesized secondary cinnamyl ethers were evaluated for Anti-Candida activity. Growth inhibition of Candida albicans ranged from 23 to 79 %. Among the 25 synthesized secondary cinnamyl ether derivatives 2e, 2h-2k, 2m, 2q, 2s 2t, and 2w-2y were found to be more effective and showed more than 50 % growth reduction at 5 mg/mL concentration.The highest activity was found for furnesol ether (79 %). Phenethyl alcohol and tertiary butyl alcohol ether derivatives showed 70 and 75 % inhibition, respectively.

Keywords

Anti-Candida Activity, Etherification, Secondary Cinnamyl Alcohols, Iodine

Title

Structural Study of PbO-PbF2-B2OGlass System Doped With V2O5 through Spectroscopic and Magnetic Properties 

Abstract

Preparation of PbO-PbF2-B2O3 glass system with different concentrations (0.1 to 0.5 mol %) of V2O5 doped into the system by reducing the corresponding mol% in V2O5 by the technique of melting and quenching. XRD (X-Ray Diffraction), SEM (Scanning Electron Microscope) and DTA (Differential Thermal Analysis) show that the prepared samples are amorphous in form. As the concentration of the dopant is increased from 0.1 to 0.3 mol% the glass forming ability of the system is increased from 0.453 to 0.561. Further increase of the dopant to 0.5 mol% the glass forming ability comedown to 0.534. The analysis of the results of these studies has been done with regard to the different oxidation states of Vanadium with the help of the data on IR (Infra Red), Optical absorption and magnetic susceptibility measureme-nts. It is observed that vanadium ions exist mainly in V4+ state and occupy tetrahedral position increasing the stability of the system, when the concentration of the dopant is increased up to 0.3 mol% and later on beyond that concentration, V5+ ions are increased at the expense of V4+. Nevertheless, in the presence of V2O5 at 0.3 mol% in the system, i) BO4 structural units are maximized and vanadium ion chiefly exists in V4+ state and occupies tetrahedral sites in the glass matrix, ii) The magnetic moment (evaluated from magnetic susceptibility) has been observed to increase to a value of 1.73 µB. These results prove that vanadium ions chiefly exist in V4+ state at 0.3 mol% range of concentration.

Keywords

PbO-PbF2-B2O3 Glass System, V2O5 Doping, Spectroscopic and Magnetic Properties